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Tuco's Headquarters was a set of rooms above a cantina where Tuco Salamanca and his crew hung out.
Walt returned to the headquarters carrying a bag of crystal, he talked his way in. When Tuco asked him his name, Walt told him "Heisenberg". When Walt demanded $50,000 Tuco laughed and threatened him, Walt then threw one of the crystals of fulminated mercury to the floor. The ensuing explosion blew out the windows ("Crazy Handful of Nothin'").
- The filming location for exterior shots of Tuco's Headquarters was 906 Park Ave SW, Albuquerque, NM 87102.